Acetylsalicylic acid organic synthesis

A wonder drug and its family To find a story that provides a thumbnail illustration for the nature and progress of worldly science, one needs to look no further than the medicine cabinet of any home.

Acetylsalicylic acid organic synthesis

Medical uses of salicylic acid Cotton pads soaked in salicylic acid can be used to chemically exfoliate skin Salicylic acid as a medication is used most commonly to help remove the outer layer of the skin. Salicylic acid was one of the original starting materials for making acetylsalicylic acid aspirin in It is also known as 2-hydroxybenzoic acid.

Salicylic acid - Wikipedia

Salicylic acid can also be prepared using the Kolbe-Schmitt reaction. Other uses[ edit ] Salicylic acid is used as a food preservativea bactericidal and an antiseptic.

Acetylsalicylic acid organic synthesis

It is easily prepared on a clean surface by spraying a saturated solution of the salt in methanol followed by evaporation. Safety[ edit ] As a topical agent and as a beta-hydroxy acid and unlike alpha-hydroxy acidssalicylic acid is capable of penetrating and breaking down fats and lipids, causing moderate chemical burns of the skin at very high concentrations.

It may damage the lining of pores if the solvent is alcohol, acetone or an oil. If high concentrations of salicylic ointment are applied to a large percentage of body surface, high levels of salicylic acid can enter the blood, requiring hemodialysis to avoid further complications.

In Arabidopsis thaliana it can be synthesized via a phenylalanine-independent pathway.


Sodium salicylate is commercially prepared by treating sodium phenolate the sodium salt of phenol with carbon dioxide at high pressure atm and high temperature K — a method known as the Kolbe-Schmitt reaction.

Acidification of the product with sulfuric acid gives salicylic acid: It can also be prepared by the hydrolysis of aspirin acetylsalicylic acid [21] or methyl salicylate oil of wintergreen with a strong acid or base.

History of aspirin White willow Salix alba is a natural source of salicylic acid HippocratesGalenPliny the Elder and others knew that willow bark could ease pain and reduce fevers. Dietary sources[ edit ] Salicylic acid occurs in plants as free salicylic acid and its carboxylated esters and phenolic glycosides.

Several studies suggest that humans metabolize salicylic acid in measurable quantities from these plants; [33] one study found that vegetarians not taking aspirin had urinary levels of salicylic acid higher than the non-vegetarians.

Indian Customs

A recent study using best practice measurement methodology significantly reduced intra-sample measurement variability but has not yet been replicated or extended. Meat, poultry, fish, eggs, oils, dairy products, sugar, cereals, and flour all have little to no salicylates. The signal can also move to nearby plants by salicylic acid being converted to the volatile ester methyl salicylate.Carboxylic acid: Carboxylic acid, any of a class of organic compounds in which a carbon atom is bonded to an oxygen atom by a double bond and to a hydroxyl group by a single bond.

Acetylsalicylic acid organic synthesis

They are generally more acidic than other organic compounds containing hydroxyl groups but are generally weaker than mineral acids such as hydrochloric acid.

Sigma-Aldrich offers a number of Acetylsalicylic acid products. View information & documentation regarding Acetylsalicylic acid, including CAS, MSDS & more. The chemical structure of the acetylsalicylic acid we produce in the lab is identical to the structure of the acetylsalicylic acid found in commercial aspiring.

This text for the two-semester introductory organic chemistry lab offers a series of clear and concise experiments that encourage accurate observation and deductive reasoning.

What is an Organic Chemical? (with pictures)

Attention: As we update our core systems, key features of the website including ordering and real-time price and availability, may be unavailable for China, India, Korea and Singapore from Friday evening, November 9th until Sunday morning November 11th. Nov 10,  · An organic chemical, also referred to as an organic compound, is defined as being constructed of molecules that possess carbon-based atoms.

Specifically, it is composed of carbon atoms attached to hydrogen atoms, together with a variety of other elements from functional groups, such as .

Sorry! Something went wrong!